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Protein design

Researchers led by University of Washington Nobel winner achieve a scientific breakthrough

A team from the University of Washington led by Nobel laureate David Baker is using artificial intelligence to design effective enzymes from scratch — an accomplishment the researchers call “one… Read More

Archon Biosciences co-founders James Lazarovits and George Ueda

Archon Biosciences emerges from stealth with $20M to create tiny ‘Antibody Cages’

Three weeks after University of Washington biochemist David Baker won a Nobel Prize, the latest venture to spin out from his lab — Archon Biosciences — has emerged from stealth… Read More

University of Washington’s David Baker wins Nobel Prize for designing proteins

University of Washington biochemist David Baker has won a share of this year’s Nobel Prize in chemistry for more than two decades of discoveries about the molecular structure of proteins… Read More

Seattle startup Arzeda raises $38M to create proteins for food, pharma, and other industries

Arzeda, a protein design startup that generates new enzymes for industrial, agricultural and other applications, announced a $38 million investment round. The Seattle-based company creates blueprints for enzymes using protein… Read More

A-Alpha Bio lands $14.5M from Department of Defense to prep for future biological threats

A-Alpha Bio will receive $14.5 million from the Department of Defense (DOD) to expand a project with a national lab to help prepare for future biological threats using the company’s… Read More

Illustration: Visualization of AI structure translated into biomolecule

Leading researchers join effort to support responsible AI for biomolecular design

More than 100 researchers — including a Nobel laureate — have signed on to a call for the scientific community to follow a set of safety and security standards when… Read More

‘The dark matter is just sitting there’: What’s standing in the way of AI for life sciences

Life scientists have a data problem: information is fragmented, siloed and incomplete. And that gets in the way of taking full advantage of using artificial intelligence technology. A panel of… Read More

Protein design and physics earn UW professors a pair of prestigious Breakthrough Prizes

Researchers at the University of Washington working on both protein design and the understanding of gravity have been awarded the Breakthrough Prize in life sciences and fundamental physics. The so-called… Read More

Virus with mini-binders

Scientists design proteins that could keep coronavirus from spreading COVID-19

Imagine being able to ward off COVID-19 just by spritzing a nasal spray into your nostrils. It may not be just your imagination: Researchers at the University of Washington have… Read More

Co-LOCKR at work

Researchers create synthetic proteins that use logic to choose which cells to kill

The age of molecular-scale computing is entering a new era, thanks to the development of a system that uses synthetic proteins and Boolean logic to identify cancer cells. The proteins… Read More

Protein structure

Scientists chart weak spots in coronavirus protein that antiviral drugs can target

Chinese researchers say they’ve mapped out a key protein structure in the virus that causes COVID-19, including the likeliest target for the antiviral drug remdesivir. What’s more, they say that… Read More

Foldit design

A protein puzzle game called Foldit turns up 99 promising ways to confound coronavirus

Who would have thought a video game could identify potential treatments for COVID-19? Researchers at the University of Washington’s Institute for Protein Design certainly thought so, and so far the… Read More

Scientists create atomic-scale map of coronavirus’ deadly weapon, pointing out a path to fighting it

Biochemists have created the first 3-D, atomic-scale map of key proteins in the killer coronavirus, opening up new possibilities for developing treatments and a vaccine. Researchers at the University of… Read More

Feng Zhang

Cyrus Biotechnology and CRISPR pioneers team up to boost gene-editing therapies

Seattle-based Cyrus Biotechnology says it’ll collaborate with the Broad Institute of MIT and Harvard on ways to optimize CRISPR gene-editing techniques for use in developing novel human therapeutics. CRISPR has… Read More

A-Alpha Bio team

A-Alpha Bio raises $2.8M for genetically engineered drug discovery platform

A Seattle startup that took root at the University of Washington has closed a $2.8 million seed round for a drug discovery platform that can sort through millions of protein… Read More

Dick's Drive-In

How a hamburger and milkshake from Dick’s Drive-In led to a breakthrough for this biotech startup

When it was time for PvP Biologics to test its promising treatment for celiac disease, the Seattle startup wanted to keep things local. They needed a meal, something that would… Read More

Institute for Protein Design wins $45M in funding from TED’s Audacious Project

The era of engineering proteins for medical applications just got a lot closer, thanks to a five-year, $45 million grant from The Audacious Project at TED to the Institute for… Read More

Protein filament

Scientists design protein filaments that snap themselves together like Lego blocks

Researchers have created molecular building blocks that can weave themselves into long threads of protein. Well, maybe not all that long. Each protein-based building block measures only a nanometer in… Read More

David Baker

Open Philanthropy Project awards $11M to protein designers for universal flu vaccine

The University of Washington’s Institute for Protein Design has won an $11.3 million grant from the Open Philanthropy Project to cook up a public health breakthrough: a universal flu vaccine.… Read More

Synthetic nucleocapsid design

Scientists steal tricks from a virus to build proteins into capsules for drug delivery

University of Washington researchers have taken a page from the viral playbook to create microscopic assemblies for packaging genetic material — with the goal of using the system for targeted drug… Read More

Cyrus Bench on laptop

Cyrus Biotech raises $8M to boost protein modeling toolkit for drug discovery

Cyrus Biotechnology is getting an $8 million infusion for its cloud-based protein modeling and design toolkit, thanks to a Series A financing round. The investment round was led by Trinity… Read More

Big data (and volunteers) help scientists solve hundreds of protein puzzles

Molecular biologists have enlisted cutting-edge trends in genomics and big data to get a grip on one of the grand challenges of biotech: figuring out how protein molecules fold. But… Read More

Protein structures

Here’s a twist: UW biochemists find clever ways to pick a protein’s pockets profitably

Researchers at the University of Washington have cracked the code for producing molecular structures with tiny pockets – structures that are likely to expand the repertoire for custom-designed proteins. The… Read More

Scientists add twists to protein designs

Biochemists from the University of Washington have engineered complex protein molecules with additional chemical bonds that make it possible to mix and match them like the base pairs of DNA.… Read More

Protein design

Designer proteins, created and edited on computers, open up new biotech frontiers

Synthetic genomes and gene editing are big things today, but the next big things in biotechnology could be proteins that are designed and edited on computers – and are then synthesized… Read More

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