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Institute for Protein Design

From Nobel buzz to hiring halt: Trump funding cuts hobble UW protein design startup machine

Since 2014, UW Medicine’s Institute for Protein Design has spun off 10 startups, and the institute’s director, University of Washington biochemist David Baker, has co-founded 21 tech companies. After Baker… Read More

Researchers led by University of Washington Nobel winner achieve a scientific breakthrough

A team from the University of Washington led by Nobel laureate David Baker is using artificial intelligence to design effective enzymes from scratch — an accomplishment the researchers call “one… Read More

Podcast

Insights from Uncommon Thinkers: How these innovators found novel approaches in their fields

This week on the GeekWire Podcast, we sit down with some of the Seattle region’s “Uncommon Thinkers” — inventors, scientists, technologists and entrepreneurs transforming industries and driving positive change in… Read More

Uncommon Thinkers: Ingrid Swanson Pultz devotes herself to improving lives through protein design

Editor’s note: This series profiles five of the Seattle region’s “Uncommon Thinkers”: inventors, scientists, technologists and entrepreneurs transforming industries and driving positive change in the world. They will be recognized Dec. 12… Read More

Archon Biosciences co-founders James Lazarovits and George Ueda

Archon Biosciences emerges from stealth with $20M to create tiny ‘Antibody Cages’

Three weeks after University of Washington biochemist David Baker won a Nobel Prize, the latest venture to spin out from his lab — Archon Biosciences — has emerged from stealth… Read More

University of Washington’s David Baker wins Nobel Prize for designing proteins

University of Washington biochemist David Baker has won a share of this year’s Nobel Prize in chemistry for more than two decades of discoveries about the molecular structure of proteins… Read More

Inside the Seattle labs of Xaira, the AI-powered startup launched with $1B from investors

In a laboratory near downtown Seattle on the shores of Lake Union, Hetu Kamisetty is helping build what he says is the biotech company of the future. If talent, money… Read More

Protein design startup Outpace lands $144M to test treatments that target solid tumors

Outpace Bio, a Seattle startup using artificial intelligence to design proteins that are incorporated into cancer therapies targeting solid tumors, has raised $144 million in new cash from investors. The… Read More

NVIDIA and top VC firms invest in Vilya, a biotech spinout from Seattle’s Institute for Protein Design

Vilya, a biotech startup built off technology developed at the Seattle-based Institute for Protein Design, announced an expanded $71 million Series A investment round. The 2-year-old company, which has operations… Read More

A-Alpha Bio lands $14.5M from Department of Defense to prep for future biological threats

A-Alpha Bio will receive $14.5 million from the Department of Defense (DOD) to expand a project with a national lab to help prepare for future biological threats using the company’s… Read More

The UW’s Institute for Protein Design keeps boosting startups, fueling AI-powered science

The University of Washington’s Institute for Protein Design is on a hot streak. New studies, companies and spinouts are emerging at a rapid clip from the research hub, propelled by… Read More

AI is boosting drug discovery and development — and sparking questions about proprietary data

The culture of collaboration in the Pacific Northwest, the impact of AI on biopharma, and the shape of new business models driven by AI were all topics at a panel… Read More

Illustration: Visualization of AI structure translated into biomolecule

Leading researchers join effort to support responsible AI for biomolecular design

More than 100 researchers — including a Nobel laureate — have signed on to a call for the scientific community to follow a set of safety and security standards when… Read More

Protein design pioneer David Baker on why sharing code is key to building biotech startups

The Institute for Protein Design at the University of Washington is a startup factory, spinning out companies developing new protein-based therapeutics, industrial enzymes, materials, biosensors and more. A key to… Read More

Univ. of Washington set to break ground on 69-acre redevelopment to create Seattle innovation hub

The University of Washington this year expects to break ground on a new building that will anchor an ambitious, innovation-focused redevelopment called Portage Bay Crossing. The project will cover 69… Read More

Tech Moves: Hootsuite adds execs; Institute for Protein Design names new leader

— Hootsuite hired two new execs: Chief Revenue Officer Jessica Hartigan and Chief Customer Officer Ellen Terchila. Hartigan previously worked at the job-seeking platform CareerBuilder for more than a decade,… Read More

Institute for Protein Design researchers show how AI can generate new protein shapes

The Institute for Protein Design helped usher in an era for scientists to predict the structure of a protein using artificial intelligence tools, an accomplishment that helped it win the… Read More

Membrane-permeable peptides

Sneaky synthetic molecules open the way for new types of drugs and a new startup

Researchers at the University of Washington have discovered how to create peptide molecules that can slip through membranes to enter cells — and they’ve also created a company with $50… Read More

Institute for Protein Design spinout Monod Bio raises $25M for molecular biosensors

The news: Monod Bio raised $25 million to develop molecular biosensors that light up when they bind their target. The sensors can be designed to detect molecules linked to disease and… Read More

Spinning out science startups: UW’s Institute for Protein Design brings research beyond ivory tower

The Institute for Protein Design is an innovation factory. Since launching a decade ago, the University of Washington institution has grown to about 200 researchers and spun out eight startups… Read More

David Baker, head of Seattle’s Institute for Protein Design, launches London biotech startup

Prolific biotech co-founder and University of Washington scientist David Baker, head of the UW Institute for Protein Design, has launched a new company. Charm Therapeutics, based in London, harnesses deep… Read More

Life sciences news: Seagen CEO resigns after arrest, cautious optimism for biotech, and more

Here’s a rundown of the top life sciences and health news across the Pacific Northwest this week. Seagen CEO resigns after domestic violence arrest: Clay Siegall resigned as CEO and… Read More

Health Innovation of the Year: 5 finalists at the GeekWire Awards span fields and approaches

The finalists for Health Innovation of the Year at the GeekWire Awards showcase the strength of science and discovery in the Pacific Northwest. Some have links to the region’s innovation… Read More

Univ. of Washington researchers find new way to design potential therapeutics

A study led by University of Washington researchers showcases a new way to generate potential drugs using computational design. The approach holds promise for accelerating the long, cumbersome and expensive… Read More

Biosensor startup Monod lands $6M and spins out of Univ. of Washington’s Institute for Protein Design

A new biotech startup has hatched from the University of Washington’s Institute for Protein Design with $6 million in funding and a leadership team fresh from Neoleukin Therapeutics, another IPD… Read More

Univ. of Washington deep learning researchers ‘hallucinate’ protein designs from scratch

New protein structures not seen in nature have emerged from deep learning software deployed by University of Washington researchers and their colleagues. The approach is a step toward building bespoke… Read More

University of Washington study: Deep learning reveals 3D models of protein machines

A new study peers into the structure of hundreds of protein complexes in cells that control everything from energy use to DNA replication. Researchers at the University of Washington’s Institute… Read More

New protein folding technology from UW lab rivals DeepMind, promises to accelerate research

The lab of David Baker at the University of Washington’s Institute for Protein Design has released its application to solve one of the toughest problems in the life sciences: how… Read More

Seattle-based Icosavax, which is developing COVID-19 vaccines, files for IPO 4 years after launch

Seattle-based Icosavax has filed to go public via an IPO, just four years after it launched out of the University of Washington. The company, a spin-out from the UW’s Institute… Read More

GeekWire Awards 2021: Learn about the 5 finalists for Innovation of the Year

Innovators across the Seattle area are tackling problems big and small with a variety of breakthroughs and technologies. Whether it’s improved battery performance, better vaccines, an easier way to purchase… Read More

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